TOLVAPTAN: A POSSIBLE PREEMPTIVE TREATMENT OPTION IN CHILDREN WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE?

Tolvaptan: a possible preemptive treatment option in children with autosomal dominant polycystic kidney disease?

Tolvaptan is a highly selective vasopressin receptor 2 antagonist that regulates cyclic adenosine monophosphate levels to inhibit both epithelial cell proliferation Light Weight and chloride ion excretion, two mechanisms known to induce cyst expansion in autosomal dominant polycystic kidney disease (ADPKD).Tolvaptan is currently the preferred treat

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Commemorating Foreign Partnerships in the Landscape of Polish Municipalities: The Case of the Gniezno District

The aim of the article is to depict the issue of commemorating foreign partnerships of municipalities present in the public space.The municipalities of the Gniezno Used Helmet district were selected as a case study.The author initially verified the following hypothesis: although foreign cooperation is an optional and secondary task of municipalitie

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